home announce activity link book home announce activity link JCCF5 JCCF7

JCCF logo Last update:
double_line
Japan Combinatorial Chemistry Focus Group

6th Conference on
Combinatorial Chemistry, Japan


April 27-28, 1998
Senri Life Science Center
Shinsenri-higashimachi 1-4-2, Toyonaka, Osaka 565, Japan

April 27 (Mon)

10:00-10:10
Opening Remark

10:10-11:00
Libraries for Origosaccharide and DNA-Cleaving Molecule By Using Liquid / Solid Phase Synthesis
(Tokyo Institute of Technology) Takashi Takahashi
11:00-11:50
New Biotechnology: Methods of Combinatorial Chemistry, Phage Display, and In Vitro Selection, and Their Target Molecules
(Konan Univ.) Naoki Sugimoto
11:50-12:15
High Throughput Screening (HTS): Key issues and the move from research style HTS to industrial style Ultra-High Throughput Screening (UHTS)
(HTS Consulting Ltd.) Jason Armstrong
12:15-14:00
Lunch & Exhibition

14:00-14:50
Integrated Instrumentation for High Throughput Organic Synthesis
(Charybdis Technologies, Inc.) Thomas J. Baiga
14:50-15:15
Small Molecule Library Synthesis with SynPhaseTM Crowns
(Chiron Technologies Pty. Ltd.) Darryl McConnell
15:15-15:55
Design of New Solid Supports for Combinatorial Chemistry
(Seoul National Univ.) Yoon-Sik Lee
15:55-16:35
Solid and Solution Phase Strategy for the Synthesis of Combinatorial Chemical Libraries
(LG Chemical Ltd.) Sang Woong Kim
16:35-17:25
EVOscreen, a Miniaturized Ultra-High Throughput Screeening System Based on Fluorescence Correlation Spectroscopy (FCS) and Additional Confocal Fluorescence Detection Methods All Having Single-Molecule Sensitivity
(EVOTEC Inc.) Timm Heinrich Jessen
18:00 Beer party

April 28 (Tue)

9:30-9:55
New Host-Guest Chemistry Using in Vitro Selection
(Nara Inst. of Science and Technology) Yoshihiro Ito
9:55-10:20
Divergent Synthesis and Biological Activities of Lipid A Analogues
(Osaka Univ.) Yoshiyuki Fukase, Masato Oikawa, Yasuo Suda, Koichi Fukase and Shoichi Kusumoto
10:20-10:45
Macrocyclization on Solid Support Using Heck Reaction
(Kyoto Pharmaceutical Univ.) Kenichi Akaji
10:45-11:10
Solid-Phase Synthesis of Dehydroalanine Derivatives
(Tanabe Seiyaku Co., Ltd) Tadatoshi Miyajima, Keiko Ohnogi, Chieko Okagaki, Masaki Yamada
11:10-11:35
A Targeted Library of Small-Molecule, Tyrosine, and Dual-Specificity Phosphatase Inhibitors Derived from a Ratinal Core Design and Random Side Chain Variation
(University of Pittsburgh, Nagoya City Univ.) Robert Rice, James Rusnak, Fumiaki Yokokawa, Shiho Yokokawa, Donald Messner, Alton Boynton, Peter Wipf and John Lazo
11:35-12:00
Improving the Efficiency of Lead Optimisation
(BioFocus) Paul Doyle
12:00-12:25
Synthesis and Purification of beta-Amino Alcohol Using "Fish Out" Method
(Kanebo Co., Ltd) Manabu Hori
12:25-14:00
Lunch & Exhibition

14:00-14:50
Prospects for Automated Synthesis
(Kyoto Univ.) Jun-ichi Yoshida
14:50-15:40
Rational Design of Combinatorial Libraries
(MSI) Robert Brown
15:40-16:30
Mass Spectrometric-Based Strategies for Characterizing and Purifyingm Combinatorial Libraries-Developments of a Multi-Column HPLC/MS System
(CombiChem, Inc.) Daniel B. Kassel
16:30-17:20
Biased Secondary Structure Mimetic Libraries for Pharmaceutical Development
(University of Washington) Michael Kahn
17:20-
Closing Remark


Contributed papers will be accepted as oral presentations. The JCCF board reserves the right to accept or reject the papers. The time for each oral presentation will be 20 minutes including discussion. All lectures and discussions will be conducted in either Japanese or English. Participants who wish to make presentation at the 6th meeting are kindly requested to notify the Secretariat before March 16, 1998 by facsimile or E-mail:

Registration fee Registration
Transportation to the conference hall
Please contact:

Question & comment: email to