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Japan Combinatorial Chemistry Focus Group

7th Conference on
Combinatorial Chemistry, Japan


September 8 - 9, 1998
Hotel KSP, KSP Hall
Sakado 3-2-1, Takatsu, Kawasaki, Japan
Dear Colleagues:

On behalf of Japan Combinatorial Chemistry Focus Group, the Organizing Committee cordially invites you to the Seventh Conference of Combinatorial Chemistry, Japan (JCCF7).

The Conference will emphasize recent major developments in the fields of combinatorial synthesis, robotic synthesis, HTS, and the various related fields.

The Conference will be held from Tuesday to Wednesday, September 8-9, 1998 at Hotel KSP, KSP Hall, Sakado 3-2-1, Takatsu-ku, Kawasaki, Kanagawa, Japan. The program will be composed of plenary and invited lectures and contributed papers. The organizing committee is intending to have about half of the invited speakers from university institutions and the other half from industrial laboratories. The conference language, written and spoken will be Japanese and/or English.

Contributed papers will be accepted as oral presentations. The JCCF board reserves the right to accept or reject the papers. The time for each oral presentation will be 20 or 30 minutes including discussion. All lectures and discussions will be conducted in either Japanese or English. Participants who wish to make presentation at the 7th meeting are kindly requested to notify the Secretariat before July 15, 1998 by facsimile or E-mail:

Title of paper
Name(s) of Author(s) [Please mark * for presenting author]
Mailing address



September 8 (Tuesday)

9:50 Opening remark
(JCCF) Takashi Takahashi
10:00 IL-01 Accelerated Lead Discovery by Automated Parallel Synthesis
(ArQule, Inc.) Paul R. Fleming
10:50 IL-02 Importance of Optimizing Pharmacokinetic Properties in the New Drug Development: Highthroughput Screening of Drug Metabolism and Transport Characteristics
(University of Tokyo) Yuichi Sugiyama
11:40 SP-01 A Solid Phase Approach to the Quinolone Antibiotics
(Argonaut Technologies) Alasdair MacDonald
12:05 Lunch & Exhibition
14:00 IL-03 Combinatorial Synthesis of Inorganic Thin Films and Devices
(Tokyo Institute of Technology) H. Koinuma,* Y. Matsumoto, M. Kawasaki, T. Fukumura, T. Ohnishi, M. Lippmaa
14:50 SP-02 Synthetic Strategy Toward Combinatorial Chemistry: Mizoroki-Heck Reaction and One-Pot Sequential Asymmetric Hydrogenation
(Tokyo Institute of Technology) Takayuki Doi,* Masaya Kokubo, Jun Watanabe, Kazuhiko Osoda, Nobuyuki Fujimoto, Takashi Takahashi
15:15 SP-03 Development of A Versatile Linker for NH in Solid Phase Synthesis
(Fujisawa Pharmaceutical Co., Ltd.,) Akito Tanaka,* Hideo Tsutsumi
15:40 SP-04 Library Synthesis and Scale up Using the Directed Sorting Technology
(IRORI Quantum) Aubrey J. Mendonca
16:05 SP-05 High-throughput Modular System for Generating and Screening Compound Libraries
(Robbins Scientific) David W. Batey
16:30 IL-04 Solution-phase Combinatorial Chemistry: Scope and Applications
(The Scripps Research Institute) Dale Boger
18:00 Beer party

September 9 (Wednesday)

09:30 IL-05 New Chemoselective Solid Phase Metalation
(Tohoku University) Yoshinori Kondo
10:20 IL-06-I SELDI (Surface Enhanced Laser Desorption/Ionization) Protein Chip Technology with Mass Spec. for Proteomics
(Ciphergen Biosystems Inc.) K. Saito
10:45 IL-06-II New techniques in solid-phase synthesis: Gaseous chemistry for parallel array synthesis
(Charybdis) Tom Baiga
11:10 SP-06 Development of Focused Library of Serine Proteases
(Molecumetics) Michael Kahn, Hiroshi Nakanishi, Takeo Harada
11:35 SP-07 Important Recent Advances in a Combinatorial Chemistry Technology Platform and Associated Informatics
(Cambridge Combinatorial) Dave Tapolczay
12:00 Lunch & Exhibition
14:15 IL-07 Polymer-Supported Carbohydrate Libraries
(Princeton Univ.) Daniel Kahne
15:05 IL-08 A New Approach to Molecular Design Based on Biomolecular Recognition Technology - Application of Phage Peptide Library -
(Otsuka Pharmaceutical Co., Ltd.) Takao Taki
15:55 SP-08 Application of HRMAS Spectroscopy and BEST-NMR Method to Combinatorial Chemistry
(Bruker Japan) Hajime Sato
16:20 IL-09 Computational Approaches to Library Design for Lead Generation, Lead@Evolution, and Lead Optimization
(CombiChem) David Spellmeyer
17:10 Closing remark
(Chairman of JCCF8) Koichi Fukase

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