8th Conference on
Combinatorial Chemistry, Japan

April 26-27, 1999
Senri Life Science Center
Shinsenri-higashimachi 1-4-2, Toyonaka, Osaka, Japan JCCF8 program is available as PDF document
PDF file: jccf8_E.pdf (Size: 8K, update: 4/13/99)

April 26 (Monday)
10:00		Opening remark
10:10-11:00	IL-1	Hirohisa Shindo (Shionogi & Co.,Ltd.)
		Development of high speed lead optimization using molecular diversity and parallel synthesis
11:00-11:20	O-1	Sally Rose (Biofocus)
		Integrating synthetic and computational chemistry for library design
11:20-11:40	O-2	Yoshihiro Ito (Nara Institute of Science and Technology)
		Extension of in vitro selection to creat new kinds of aptamers and aptazymes
11:40-13:30		Lunch & Exhibition
13:30-14:20	IL-2	Kazuhisa Sugimura (Faculty of Technology, Kagoshima University)
		Peptide mimics of the CTLA4 or CCR5-binding domain and their biological functions
14:20-14:40	O-3	Yasuyuki Shimohigashi (Graduate School of Science, Kyushu University)
		Sturucture-activity Studies of Phospholipase A2 Inhibitors Based on Peptide Library
14:40-15:00	O-4	Shinji Nagai (Hitachi, Ltd.)
		Work flow of combinatorial synthesis using liquid synthesis and parallel purifier
15:00-15:20	O-5	Michiko Kanai^* (Nihon Waters K.K.), Andrew Brailsford and Chris Chumsae (Waters Corporation)
		Mass-directed auto purification and characterization of combinatorial libraries
15:20-15:50		Coffee break
15:50-16:40	IL-3	Anthony D. Piscopio (Array BioPharma)
		New methods for the high speed parallel synthesis of functionalized heterocycles
16:40-17:00	O-6	Patrick Coffey (Dyax Corporation, Biotage Division)
		High throughput organic chemistry (HTOC): An automated system for purifying, characterizing and quantifying products of automated synthesis
17:00-17:50	IL-4	Shu Kobayashi (Graduate School of Pharmaceutical Sciences, University of Tokyo)
		Organic synthesis for library construction
18:00-		Mixer

April 27 (Tuesday)
9:30-10:20	IL-5	Tsutomu Nakamura (Osaka National Research Institute, AIST), Masahiro Iwakura (National Institute of Bioscience and Human Technology, AIST)
		Discrimination of structural and functional elements in proteins by circular permutation analysis
10:20-10:40	O-7	*T. S. Haque¹, A. G. Skillman², C. E. Lee¹, H. Habashita^1, I. Y. Gluzman³, T. J. A. Ewing², D. E. Goldberg³, I. D. Kunz², J. A. Ellman¹**(1. University of California, Berkeley; 2. University of California, San Francisco; 3. Washington University)
		Directed combinatorial library of aspartyl protease inhibitors. Application to discovery of non-peptide inhibitors of malarial aspartylprotease plasmepsin II.
10:40-11:00	O-8	Jason Armstrong (HTS Consulting Ltd.)
		Comparisons of HTS mRNA assays that are alternatives to reporter assays, including their implementation of automation.
11:00-11:50	IL-6	Sung-eun Yoo (Korea Research Institute of Chemical Technology)
		Design of new linkers and a new analytical methodology for combinatorial chemistry
11:50-13:50		Lunch & Exhibition
13:50-14:10	O-9	*Takayuki Doi, Ichiro Hijiguro^, Takashi Takahashi** (Department of Chemical Engineering, Tokyo Institute of Technology)
		An efficient solid phase synthesis of the vitamin D₃ system
14:10-15:00	IL-7	Jonathan A. Ellman (University of California, Berkeley)
		Design, synthesis and evaluation of small molecule libraries
15:00-15:20	O-10	*Yasuhiro Uozumi, Tetsu Nakane^, H. Peter Nestler, Rosemarie Sherlock, Ruiping Liu** (Nagoya City University, Cold Spring Harbor Laboratory)
		A combinatorial approach to enantioselectors for axially chiral phosphines
15:20-15:40	O-11	Clare Ruddick (Mettler Toledo Myriad)
		High performance automated synthesis successful advanced chemistry in an integrated system
15:40-16:30	IL-8	Chi-Huey Wong (The Scripps Research Institute)
		Libraries of carbohydrates and carbohydrate mimetics
16:30		Closing remark

Contributed papers

Dr. Koichi Fukase
Conference Director of JCCF8
Department of Chemistry, Graduate school of Science, Osaka University
Machikaneyama 1-1, Toyonaka, Osaka 560-0043, Japan
FAX: +81-6-6850-5419 (as of 1/1/1999)

Title of paper

Name(s) of Author(s) (Please mark * for presenting author)

e-mail

March 20, 1999

April 5, 1999

Instruction to Contributors

Conference Language

The conference language, written and spoken will be Japanese and/or English. Registration fee

Advance registration

associate member: free until 3 persons (An associate member shall pay 100,000 Yen a unit per year. Only associate members can exhibit during the JCCF meetings.)
regular member: commercial 15,000 yen; academic, government, public 8,000 yen; student 3,000 yen (A member shall pay 5,000 Yen per year. A student member shall pay 3,000 Yen per year.)
member of co-sponsors (e.g., Chemical Society of Japan, Pharmaceutical Society of Japan, etc.): commercial 20,000 yen; academic, government, public 10,000 yen; student 4,000 yen
without membership: 30,000 yen

On-site or late registration

regular member: commercial 20,000 yen; academic, government, public 10,000 yen; student 4,000 yen.
member of co-sponsors: commercial 25,000 yen; academic, government, public 12,000 yen; student 6,000 yen
without membership: 40,000 yen

Registration

Name	__________, __________, _____ (Family name), (First name), (Middle name)
Affiliation
Mailing address
Phone
FAX
E-MAIL
Remittance	____,____ yen
I have instructed my bank, ____________ on mm/dd/yy to make a payment of conference fee.

Name of Bank	Sakura Bank, Higobashi Branch
Account No.	(Regular Savings) 3464685
Account Name	Japan combinatorial chemistry focus group (JCCF)

Transportation to the conference hall

Take a direct flight to Osaka (Kansai) International Airport (KIX), from where JR train "Haruka" will reach JR Shin-Osaka Station, take the subway Midosuji-line for Senri-chuo station, then 5min on foot.
Take Osaka monorail to Senri-chuo station from Osaka Domestic Airport where some domestic flights come from New Tokyo International Airport (Narita).

Correspondence

Dr. Koichi Fukase
Conference Director of JCCF8
Department of Chemistry, Graduate school of Science, Osaka University
Machikaneyama 1-1, Toyonaka, Osaka 560-0043, Japan
FAX: +81-6-6850-5419 (as of 1/1/1999)
e-mail:

Question & comment: email to

8th Conference on Combinatorial Chemistry, Japan

8th Conference on
Combinatorial Chemistry, Japan