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Japan Combinatorial Chemistry Focus Group

16th Conference on
Combinatorial Chemistry, Japan


April 21-22, 2003
Senri Life Science Center
Shinsenri-higashimachi 1-4-2, Toyonaka, Osaka, Japan
Invitation
On behalf of Japan Combinatorial Chemistry Focus Group, the Organizing Committee cordially invites you to the 16th Conference on Combinatorial Chemistry, Japan (JCCF16).

Sponsored by: The Japan Combinatorial Chemistry Focus Group
Supported by: Synthetic Organic Chemistry, Japan

The Chemical Society of Japan

The Pharmaceutical Society of Japan
The Conference will emphasize recent major developments in the fields of combinatorial synthesis, robotics synthesis, HTS, and the various related fields.

Transportation to the conference hall


April 21 (Monday)
9:30 Opening
9:40-10:30IL-1Peter Cohan, Peter J. Desrosiers* (SYMYX)
High Throughput Exploration of the Physical and Chemical Properties of Materials
10:30-11:20IL-2Ryu Ilhyong (Osaka Prefecture University)
New Synthetic Methods Based on Characteristics of Fluorous Media
11:20-13:10 Lunch & Exhibition
13:10-14:00IL-3Mark R. Player,* Anne L. Vergnon, Richard S. Pottorf (3-Dimensional Pharmaceuticals)
Design of GPCR-targeted Libraries Using Privileged Molecular Fragments
14:00-14:50IL-4Yohei Hirai,* Yumiko Oka (Sumitomo Electric)
Generation of peptide derivatives for hair follicle regeneration -Application of a morphoregulatory protein epimorphin-
14:50-15:15O-1Hideaki Hioki,* Miwa Kubo, Emi Nashomoto, Hiroko Yoshida, Motohiko Bando, Yumiko Ohnishi, Mitsuaki Kodama (Tokushima Bunri University)
Synthesis of fluorescence-labeled peptidocalix[4]arene library and its peptide sensing ability
15:15-15:40O-2Tatsuya Zenkoh,1* Hiroyuki Setoi,1 Hiroshi Tanaka,2 Takashi Takahashi2 (Fujisawa Pharmaceutical Co.,Ltd,1 Tokyo Institute of Technology2)
Solid-Phase Synthesis of a Focused Library based on 4'-Dehydroxyphlorizin
15:40-16:10 Coffee Break
16:10-16:35O-3Lewin Wint, Theirry Boxus, Susan Williams,* Ben Moshiri (Mettler-Toledo AutoChem)
Solution Phase Synthesis and Work-up Using an Integrated Approach
16:35-17:00O-4Niamh X. Cawley,1 Masao Chino,2* Masahiro Wakao,2 Alex Maldonado,1 Yazmin M. Rodriguez,1 Y. Peng Loh,1 Jonathan A. Ellman2 (National Institutes of Health1 University of California, Berkeley2)
Synthesis and Characterization of the First Potent Inhibitor of Yapsin 1
17:00-18:00IL-5Burkhard Fleckenstein,1* Karl-Heinz Wiesmüller,2 Günther Jung3 (University of Oslo,1 EMC microcollections GmbH,2 Eberhard Karls Universität Tübingen3)
Combinatorial Approaches for the Elucidation of the Molecular Interactions in T cell mediated Immune Response
18:00- Mixer

April 22 (Tuesday)
9:00-9:25O-5Shahnaz Ghassemi, Omar Mneimne,* Peter Rahn, Jack Liu, Michael Webb (Biotage)
Novel Synthesis and Purification Methodology using Silica-based Media in a Cartridge Format
9:25-9:50O-6Shin-ichi Kusaka,* Suguru Dohi, Takayuki Doi, Takashi Takahashi (Tokyo Institute of Technology)
Synthesis of Macrosphelide Library Utilizing Palladium-catalyzed Carbonylation
9:50-10:15O-7Thomas Schwalbe (CPC Systems GmbH)
Application of microreactors for the sequential synthesis of combinatorial libraries
10:15-11:05IL-6Shigeyuki Fukui (Kyoto Sangyo University)
Oligosaccharide microarrays toward high-throughput detection of carbohydrate-protein interactions and determination of specificities
11:05-13:45 Lunch & Exhibition
13:45-14:35IL-7Reiko Iwase,1* Akira Murakami2 (Teikyo University of Science and Technology,1 Kyoto Institute of Technology2)
Development of functional oligosaccharide analogues for their application to gene regulation and detection
14:35-15:00O-8Zemin Wu,* Nicholas J. Ede (Mimotopes Pty.)
Arylnitro-reduction Promoted Solid-phase Synthesis of Heterocycles on SynPhase™ Lanterns
15:00-15:25O-9Osamu Shimomura,1* Bruce Clapham,2 Carsten Spanka,2 Suresh Mahajan,2 Kim D. Janda2 (Osaka Institute of Technology,1 The Scripps Research Institute2)
Synthesis and Application of Novel Polystyrene Resin Supports for Organic Synthesis
15:25-15:50O-10Masato Matsuoka,1* Steven V.Ley2 (Nippon Shinyaku Co.,1 University of Cambridge2)
Polymer-Supported Reagents and Scavengers for Multi-step Organic Synthesis: Application to the Synthesis of Nicotine Derivatives
15:50-16:50IL-8M. Meldal,* P. St. Hilaire, M. Grötli, J. Rademan, C. Christensen, C. Tornøe, J. Beyer, T. E. Nielsen, F. Diness, C. Gotfredsen, R. Michael, T. Schulte-Herbrüggen (Carlsberg Laboratory)
Integrated Solid Phase Combinatorial Chemistry: Supports, Synthesis, Assay Development and Single Bead Analysis
16:35
Closing Remark

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