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Japan Combinatorial Chemistry Focus Group

18th Conference on
Combinatorial Chemistry, Japan

On behalf of Japan Combinatorial Chemistry Focus Group, the Organizing Committee cordially invites you to the 18th Conference on Combinatorial Chemistry, Japan (JCCF18).

Sponsored by:	The Japan Combinatorial Chemistry Focus Group
Supported by:	Synthetic Organic Chemistry, Japan
	The Chemical Society of Japan
	The Pharmaceutical Society of Japan

The Conference will emphasize recent major developments in the fields of combinatorial synthesis, robotics synthesis, HTS, and the various related fields.

Transportation to the conference hall

Take a direct flight to Osaka (Kansai) International Airport (KIX), from where JR train "Haruka" will reach JR Shin-Osaka Station, take the subway Midosuji-line for Senri-chuo station, then 5min on foot. Take Osaka monorail to Senri-chuo station from Osaka Domestic Airport where some domestic flights come from New Tokyo International Airport (Narita).

Monday, April 26
9:50		Opening Remark
10:00-10:50	IL-1	Dennis P. Curran (University of Pittsburgh) Fluorous Mixture Synthesis of Natural Product Libraries
10:50-11:10	O-1	Jennifer V. Smith,* Terry A. Berger, Kimber Fogelman, and Rick Wikfors (Mettler-Toledo Autochem) Screening and Purification of Compounds Using SFC/MS, Linkware and SFC AutoPrep
11:10-11:30	O-2	Kiyoshi Nokihara,* Takafumi Ohyama, Koichi Yonemura, Shizue Yomamoto, Nahoko Sugioka, Noriko Ono (HiPep Laboratories) Development of Simple and Low Cost Manual Synthesizers for Chemical Library Construction
11:30-13:10		Lunch & Exhibition
13:10-13:55	IL-2	Yoon-Sik Lee (Seoul National University) Microsystems for Peptide Array Synthesis and Bioassay
13:55-14:15	O-3	Yoichiro Hoshina,* Hiroyuki Mogi, Takayuki Doi, Hiroshi Tanaka, Yoshifumi Yamada, Takashi Nagano, Takashi Takahashi (Tokyo Institute of Technology; Olympus Corporation) A Synthesis of Natural Product Like Library: Combinatorial Synthesis of Aeruginosin Analogues
14:15-14:35	O-4	Tsutomu Mukade,* Peter Steck, Cleo M. Salisbury, Dustin J. Maly, Jonathan A. Ellman (University of California, Berkeley) Determination of Protease Substrate Specificity Using Peptide Microarrays
14:35-14:55	O-5	Mitsuhiro Moriwaki,* Hiroshi Tanaka, Takashi Takahashi (Tokyo Institute of Technology, Toray Industries Inc.) Solid-Phase Synthesis of Symmetric and Asymmetric Norbinaltorphimine Libraries
14:55-15:30		Break
15:30-15:50	O-6	Behrooz H. Yousefi,* Nikolay Yu. Gorobets, C. Oliver Kappe (Karl-Franzens-University Graz, Viena Univ. of Technology) Rapid Microwave-Assisted Solution Phase Synthesis of Substituted 2-Pyridinone Libraries
15:50-16:10	O-7	Neil V. Harris (Argenta Discovery Ltd and Aventis Pharmaceuticals Ltd.) The Discovery of IVL-745 -A Clinical Candidate Discovered Solely Using Solid-Phase Combinatorial Chemistry
16:10-16:30	O-8	Masato Oikawa,* Yoshiyuki Takeda, Minoru Ikoma, and Makoto Sasaki (Tohoku University) Organic Synthesis on Soluble Polymer Support and Its Use for Small Molecule Libraries
16:30-17:20	IL-3	Yoshiaki Kiso (Center for Frontier Research in Medicinal Science, Kyoto Pharmaceutical University) Design and Synthesis of Peptidomimetic Inhibitors of Aspartic Proteases
18:00-		Mixer
Tuesday, April 27
9:30-10:20	IL-4	C. Oliver Kappe (Karl-Franzens-University Graz) High-Speed Microwave Chemistry: Enabling Technology in Solution and Solid-Phase Combinatorial Chemistry
10:20-11:05	IL-5	John A. Robinson (University of Zurich) Design, Synthesis, and Applications of Protein Epitope Mimetics
11:05-11:25	O-9	Takeharu Haino,* Hisashi Mitsuhashi, Nobue Nagai, Yoshimasa Fukazawa (Hiroshima University) Combinatorial Chemistry for Evaluation of Host-Guest Interaction
11:25-11:45	O-10	Tamas Nagy, Janos Gerencser, Gyorgy Dorman, Laszlo Urge,* Ferenc Darvas (ComGenex, Inc.) Novel Solution-Phase Combinatorial Libraries Based on Meldrum's Acid
11:45-13:35		Lunch & Exhibition
13:35-14:20	IL-6	Kuiling Ding (Shanghai Institute of Organic Chemistry) Combinatorial Approach to Chiral Catalyst Engineering and Screening: Rational Design and Serendipity
14:20-14:40	O-11	Nicholas J. Ede,* Saman Sandanayake, Seneka Perera, Philip Rea (Mimotopes Pty. Ltd.) Utilizing SynPhaseTM Scavenger Lantern Technology for the Synthesis of Small Molecule Combinatorial Libraries via Solution-Phase Methodologies
14:40-15:00	O-12	Vijay Gupta (Biotage AB) Highly Efficient and Automated Microwave Assisted Organic Synthesis for Diverse Library Synthesis
15:00-15:45	IL-7	Johannes G. de Vries,* Laurent Lefort, Andr_ H. M. de Vries, Jeroen A. F. Boogers (DSM Pharma Chemicals) Combinatorial Approaches to Asymmetric Hydrogenation Based on Monodentate Phosphoramidites
15:45-16:35	IL-8	Yasuyuki Kita (Osaka University) Environmentally Benign Organic Synthesis Using Hypervalent Iodine Reagents

Contributed papers

Contributed papers will be accepted as oral presentations. The organizing committee reserves the right to accept or reject papers. The time for each oral presentation will be 20 or 30 minutes including discussion. Presenters are requested to use OHP or PC projector (35 mm slide projector is not available).
Participants who wish to present a paper should send following information to Conference Director of JCCF18 (shown at the bottom of this page) via e-mail from Monday, January 5 to Saturday, February 7, 2004.



	1	Title of paper
	2	Name(s) of Author(s) (Please mark * for presenting author)
	3	Affiliation
	4	Audio-Visual requirements: OH projector and/or PC projector
	5	Presenting author's		address
	6			phone
	7			fax
	8			e-mail

Presenters are requested to supply an abstract by Saturday, March 6, 2004. Presenters must conform to the Instruction to Contributors(inst_E.pdf).
Presenter is exempted from conference registration fee.

The conference language, written and spoken will be Japanese and/or English.

Advance registration (by Thursday, April 15, 2004)
1. associate member: free up to 3 people (An associate member shall pay 100,000 Yen a unit per year. Only associate members can exhibit during the JCCF meetings.)
2. regular member: commercial 15,000 yen; academic, government, public 3,000 yen; student free (A member shall pay 5,000 Yen per year. A student member shall pay 3,000 Yen per year.)
3. member of co-sponsors (e.g., Chemical Society of Japan, Pharmaceutical Society of Japan, etc.): commercial 20,000 yen; academic, government, public 5,000 yen; student 1,000 yen
4. without membership: 30,000 yen
On-site or late registration
1. regular member: commercial 20,000 yen; academic, government, public 5,000 yen; student 1,000 yen.
2. member of co-sponsors: commercial 25,000 yen; academic, government, public 7,000 yen; student 2,000 yen
3. without membership: 40,000 yen

Those who wish to participate in the Conference are kindly requested to register in advance. Please complete Form(RegForm_E.pdf) and send it by FAX to JCCF Society Office (shown at the bottom of this page) or send following information via e-mail from Monday, January 5 to Thursday, April 15, 2004 (for advance registration).


1. Name
2. Affiliation
3. Address
4. Phone
5. Fax
6. E-mail
7. Amount remitted (in Yen)
8. Bank instructed
9. Date of remittance

Registration fee must be received prior to the conference.
Payment of the registration fee should be made in Japanese Yen by bank transfer to:

• Name of Bank: Sumitomo Mitsui Bank, Nakanoshima Branch
  
• Account No: (Regular Savings) 3464685
  
• Account Name: Japan Combinatorial Chemistry Focus Group (JCCF)
  

Conference Director


Dr. Satoshi Minakata
Department of Materials Chemistry, Graduate School of Engineering, Osaka University
2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
FAX: +81-6-6879-7402
E-mail:


Registration


JCCF Society Office
FAX: +81-3-3292-7622
E-mail: