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Japan Combinatorial Chemistry Focus Group

19th Conference on
Combinatorial Chemistry, Japan


September 13-14, 2004
KSP Hall (3F, Hotel KSP)
Kanagawa Science Park, Sakado 3-2-1, Takatsu-ku, Kawasaki, Kanagawa, Japan
Invitation
On behalf of Japan Combinatorial Chemistry Focus Group, the Organizing Committee cordially invites you to the 19th Conference on Combinatorial Chemistry, Japan (JCCF19).

Sponsored by: The Japan Combinatorial Chemistry Focus Group
Supported by: Synthetic Organic Chemistry, Japan

The Chemical Society of Japan

The Pharmaceutical Society of Japan
The Conference will emphasize recent major developments in the fields of combinatorial synthesis, robotics synthesis, HTS, and the various related fields.

Transportation to the conference hall

From Tokyo International Airport, take the JR train "Narita Express" to JR Tokyo Station (63 min). Take the Marunouchi subway line for Otemachi station (2 min), and change to Hanzomon Line for Chuo-Rinkan via Shibuya.


Monday, September 13
9:50Opening Remark
10:00-11:00IL-1Mario H. Geysen (University of Virginia)
A Combinatorial approach to Reaction Optimization, Reaction Screening and the Discovery of Novel Chemical Reactions
11:00-11:25O-1Aubrey Mendonca1*, Alasdair MacDonald1, Andrew Coffey2, John Davies2, Paul Boguszewski2, John OfBrien1 and Frank Warner2 (1Polymer Laboratories Inc.,2Polymer Laboratories Ltd.)
m-PlugsTM: Improved Tools for High Throughput Chemistry
11:25-11:50O-2Osamu Shimomura,* KosukeTayama, Ryoki Nomura (Osaka Institute of Technology)
Application of Aryl Sulfide as a Novel Safety Catch Linker for Solid Phase Organic Synthesis
11:50-14:00Lunch & Exhibition
14:00-15:00IL-2Stephen L. Buchwald (Massachusetts Institute of Technology)
Progress in metal-catalyzed cross coupling reactions
15:00-15:25O-3Kazuhiro Chiba*, Shokaku Kim, Kanako Hayashi, Masayoshi Shimizu, Yoshikazu Kitano, Masahiro Tada (Tokyo University of Agriculture and Technology)
Chemical reactions in cyclohexane-based phase-separable organic solutions
15:25-15:50O-4Lajos Godorhazy1, Daniel Szalay1, Gabor Panka1, Agota Bucsai2, Gyorgy Dorman2, Laszlo Urge1,2* and Ferenc Darvas1,2 (1Thales, Inc., 2ComGenex, Inc.)
Application of a microchannel flow reactor for parallel hydrogenation
15:50-16:00Break
16:00-16:25O-5Jennifer Smith,* Terry A. Berger, Kimber Fogelman, and Rick Wikfors (Mettler-Toledo AutoChem)
Use of SFC/MS for Screening Compounds and PrepSFC for High Thru put Purification
16:25-16:50O-6Hiroshi Tanaka, Yuki Iwata,* Daisuke Takahashi, Masaatsu Adachi, Takashi Takahashi (Tokyo Institute of Technology)
Efficient Stereoselective Synthesis of N-Linked Glycopeptides by N-Glycosylation of Primary Amide Groups
16:50-17:50IL-3Takehiko Kitamori (The University of Tokyo)
Micro Chemical & Bio Systems and High Though Put Processes
18:00-Mixer

Tuesday, September 14
9:00-9:50IL-4Itaru Hamachi (Kyushu Univeristy)
Semi-wet Supramolecular Materials Obtained by Solid Phase Synthesis
9:50-10:40IL-5Hisakazu@Mihara (Tokyo Institute of Technology)
Development of protein detection chips using designed peptide microarrays
10:40-11:05O-7Naoki Kanoh,* Kaori Honda, Aya Asami, Saori Kumashiro, Siro Simizu, Takemichi Nakamura, Yasumitsu Kondoh, Tomoyuki Amemiya, Satoru Hatakeyama, Hideo Tashiro, and Hiroyuki Osada (Discovery Research Institute, RIKEN)
Photo-Crossinked Small Molecule Microarrays: Concept, Scope, and Limitation
11:05-11:30O-8Yoshihiro Ito,* Tsuyoshi Ohta, Miyuki Omura, Kaoru Omura (Kanagawa Academy of Science and Technology, RIKEN)
Development of everything microarray using photo-immobilization method
11:30-13:00Lunch & Exhibition
13:00-14:00IL-6Nobutaka Fujii (Kyoto University)
Peptide-lead Drug Templates for Genome-lead Drug Discovery
14:00-14:25O-9Thomas Schwalbe, Gerhard Jas (Cellular Process Chemistry, Inc.)
Sequential organic synthesis in microreactors - a new versatile tool for easy access to libraries and building
14:25-15:15IL-7Horst D. Ambrosi, Christian Mang, Stefan Schunk, Oliver Schwarz, and Jasmin Jakupovic (AnalytiCon Discovery GmbH)
Natural Product Based Libraries
15:15-15:40O-10Hiroshi Tanaka,* Tetsuya Zenkoh, Hidetaka Hatori, Motoo Kobayashi, Makoto Hasegawa, Mamoru Hatakeyama, Hiroyuki Setoi, Haruma Kawaguchi, Hiroshi Handa, and Takashi Takahashi (Tokyo Institute of Technology, Keio University, Fujisawa pharmaceutical Co. Ltd.)
Combinatorial Synthesis of FR225659 libraries and Its Receptor Screening Using Affinity Latex particles
15:40-16:40IL-8Julius Rebek Jr. (The Scripps Research Institute)
Molecular Recognition on Concave and Convex Surface
16:40-Closing Remark

Contributed papers

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